ARTICLES:

L Mao and AA Abdel-Rahman

Synergistic behavioral interaction between ethanol and clonidine in rats: role of alpha-2 adrenoceptors
J Pharmacol Exp Ther 1996 279: 443-449. [Abstract] [PDF]  

IN MEMORIAM
J Pharmacol Exp Ther 1996 279: 443. [Abstract] [PDF]  

WB Pickworth, RV Fant, MF Butschky, and JE Henningfield

Effects of transdermal nicotine delivery on measures of acute nicotine withdrawal
J Pharmacol Exp Ther 1996 279: 450-456. [Abstract] [PDF]  

YN Wu and SW Johnson

Pharmacological characterization of inward current evoked by N-methyl-D- aspartate in dopamine neurons in the rat brain slice
J Pharmacol Exp Ther 1996 279: 457-463. [Abstract] [PDF]  

T Joseph, C Coirault, L Ducros, and Y Lecarpentier

Mechanical and energetic effects of cromakalim on guinea pig left ventricular papillary muscle
J Pharmacol Exp Ther 1996 279: 464-471. [Abstract] [PDF]  

C Blaya, J Crespo, A Crespo, and SF Alino

Anti-interleukin 4 antibody and indomethacin synergistic effect on B16 melanoma tumor progression
J Pharmacol Exp Ther 1996 279: 472-477. [Abstract] [PDF]  

TA Slotkin, L Thai, EC McCook, JL Saleh, J Zhang, and FJ Seidler

Aging and glucocorticoids: effects on cell signaling mediated through adenylyl cyclase
J Pharmacol Exp Ther 1996 279: 478-491. [Abstract] [PDF]  

LJ Bristow, PH Hutson, JJ Kulagowski, PD Leeson, S Matheson, F Murray, D Rathbone, KL Saywell, L Thorn, AP Watt, and MD Tricklebank

Anticonvulsant and behavioral profile of L-701,324, a potent, orally active antagonist at the glycine modulatory site on the N-methyl-D- aspartate receptor complex
J Pharmacol Exp Ther 1996 279: 492-501. [Abstract] [PDF]  

YA Kolesnikov, S Jain, R Wilson, and GW Pasternak

Peripheral morphine analgesia: synergy with central sites and a target of morphine tolerance
J Pharmacol Exp Ther 1996 279: 502-506. [Abstract] [PDF]  

J Yu, ER Butelman, JH Woods, BT Chait, and MJ Kreek

In vitro biotransformation of dynorphin A (1-17) is similar in human and rhesus monkey blood as studied by matrix-assisted laser desorption/ionization mass spectrometry
J Pharmacol Exp Ther 1996 279: 507-514. [Abstract] [PDF]  

FA Boeckman and E Aizenman

Pharmacological properties of acquired excitotoxicity in Chinese hamster ovary cells transfected with N-methyl-D-aspartate receptor subunits
J Pharmacol Exp Ther 1996 279: 515-523. [Abstract] [PDF]  

SL Walsh, JT Sullivan, KL Preston, JE Garner, and GE Bigelow

Effects of naltrexone on response to intravenous cocaine, hydromorphone and their combination in humans
J Pharmacol Exp Ther 1996 279: 524-538. [Abstract] [PDF]  

JY Xu, A Seyed-Mozaffari, S Archer, and JM Bidlack

N-cyclobutylmethyl analog of normorphinone, N-CBM-TAMO: a short-term opioid agonist and long-term Mu-selective irreversible opioid antagonist
J Pharmacol Exp Ther 1996 279: 539-547. [Abstract] [PDF]  

L Trumper, LA Monasterolo, and MM Elias

Nephrotoxicity of acetaminophen in male Wistar rats: role of hepatically derived metabolites
J Pharmacol Exp Ther 1996 279: 548-554. [Abstract] [PDF]  

MH Holtmann, EM Hadac, CD Ulrich, and LJ Miller

Molecular basis and species specificity of high affinity binding of vasoactive intestinal polypeptide by the rat secretin receptor
J Pharmacol Exp Ther 1996 279: 555-560. [Abstract] [PDF]  

W Loscher, C Rundfeldt, D Honack, and U Ebert

Long-term studies on anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. I. Comparison of diazepam, clonazepam, clobazam and abecarnil
J Pharmacol Exp Ther 1996 279: 561-572. [Abstract] [PDF]  

W Loscher, C Rundfeldt, D Honack, and U Ebert

Long-term studies on anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. II. The novel imidazoquinazolines NNC 14-0185 and NNC 14-0189
J Pharmacol Exp Ther 1996 279: 573-581. [Abstract] [PDF]  

BD Waterhouse, EM Gould, and I Bekavac

Monoaminergic substrates underlying cocaine-induced enhancement of somatosensory-evoked discharges in rat barrel field cortical neurons
J Pharmacol Exp Ther 1996 279: 582-592. [Abstract] [PDF]  

JP Kukkonen, J Nasman, P Ojala, C Oker-Blom, and KE Akerman

Functional properties of muscarinic receptor subtypes Hm1, Hm3 and Hm5 expressed in Sf9 cells using the baculovirus expression system
J Pharmacol Exp Ther 1996 279: 593-601. [Abstract] [PDF]  

LA Monasterolo, L Trumper, and MM Elias

Effects of gamma-aminobutyric acid agonists on the isolated perfused rat kidney
J Pharmacol Exp Ther 1996 279: 602-607. [Abstract] [PDF]  

G Jr Pugh, PB Smith, DS Dombrowski, and SP Welch

The role of endogenous opioids in enhancing the antinociception produced by the combination of delta 9-tetrahydrocannabinol and morphine in the spinal cord
J Pharmacol Exp Ther 1996 279: 608-616. [Abstract] [PDF]  

Y Watanabe, Y Hara, M Tamagawa, and H Nakaya

Inhibitory effect of amiodarone on the muscarinic acetylcholine receptor-operated potassium current in guinea pig atrial cells
J Pharmacol Exp Ther 1996 279: 617-624. [Abstract] [PDF]  

BS Chan, VA Lazzaro, JP Seale, and GG Duggin

Transport of paraquat in a renal epithelial cell line LLC-PK1
J Pharmacol Exp Ther 1996 279: 625-632. [Abstract] [PDF]  

AM Mayer, S Brenic, and KB Glaser

Pharmacological targeting of signaling pathways in protein kinase C- stimulated superoxide generation in neutrophil-like HL-60 cells: effect of phorbol ester, arachidonic acid and inhibitors of kinase(s), phosphatase(s) and phospholipase A2
J Pharmacol Exp Ther 1996 279: 633-644. [Abstract] [PDF]  

MJ Currens, RJ Gulakowski, JM Mariner, RA Moran, RW Jr Buckheit, KR Gustafson, JB McMahon, and MR Boyd

Antiviral activity and mechanism of action of calanolide A against the human immunodeficiency virus type-1
J Pharmacol Exp Ther 1996 279: 645-651. [Abstract] [PDF]  

MJ Currens, JM Mariner, JB McMahon, and MR Boyd

Kinetic analysis of inhibition of human immunodeficiency virus type-1 reverse transcriptase by calanolide A
J Pharmacol Exp Ther 1996 279: 652-661. [Abstract] [PDF]  

JS Kreeger and AA Larson

The substance P amino-terminal metabolite substance P(1-7), administered peripherally, prevents the development of acute morphine tolerance and attenuates the expression of withdrawal in mice
J Pharmacol Exp Ther 1996 279: 662-667. [Abstract] [PDF]  

H Xie, I Laher, and JA Bevan

Protein kinase C modulates flow-initiated contraction
J Pharmacol Exp Ther 1996 279: 668-674. [Abstract] [PDF]  

Y Masuda, T Sugo, T Kikuchi, A Kawata, M Satoh, Y Fujisawa, Y Itoh, M Wakimasu, and T Ohtaki

Receptor binding and antagonist properties of a novel endothelin receptor antagonist, TAK-044 [cyclo[D-alpha-aspartyl-3-[(4- phenylpiperazin-1-yl) carbonyl]-L-alanyl-L-alpha-aspartyl-D-2-(2- thienyl) glycyl-L-leucyl-D-tryptophyl]disodium salt], in human endothelinA and endothelinB receptors
J Pharmacol Exp Ther 1996 279: 675-685. [Abstract] [PDF]  

AW Fox, BW Sullivan, JD Buffini, ML Neichin, R Nicora, FK Hoehler, R O'Rourke, and RR Stoltz

Reduction of serum lactate by sodium dichloroacetate, and human pharmacokinetic-pharmacodynamic relationships
J Pharmacol Exp Ther 1996 279: 686-693. [Abstract] [PDF]  

JE Piletz, H Zhu, and DN Chikkala

Comparison of ligand binding affinities at human I1-imidazoline binding sites and the high affinity state of alpha-2 adrenoceptor subtypes
J Pharmacol Exp Ther 1996 279: 694-702. [Abstract] [PDF]  

NJ Brown, D Ryder, JV Gainer, JD Morrow, and J Nadeau

Differential effects of angiotensin converting enzyme inhibitors on the vasodepressor and prostacyclin responses to bradykinin
J Pharmacol Exp Ther 1996 279: 703-712. [Abstract] [PDF]  

LM Kamendulis, MR Brzezinski, EV Pindel, WF Bosron, and RA Dean

Metabolism of cocaine and heroin is catalyzed by the same human liver carboxylesterases
J Pharmacol Exp Ther 1996 279: 713-717. [Abstract] [PDF]  

JG Gerber and NA Payne

Secretin inhibits canine gastric acid secretion in response to pentagastrin by modulating gastric histamine release
J Pharmacol Exp Ther 1996 279: 718-723. [Abstract] [PDF]  

Y Masubuchi, S Igarashi, T Suzuki, T Horie, and S Narimatsu

Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate
J Pharmacol Exp Ther 1996 279: 724-731. [Abstract] [PDF]  

EM Kudlacz, RW Knippenberg, DE Logan, and TP Burkholder

Effect of MDL 105,212, a nonpeptide NK-1/NK-2 receptor antagonist in an allergic guinea pig model
J Pharmacol Exp Ther 1996 279: 732-739. [Abstract] [PDF]  

KS Hsu, CC Huang, MT Su, and JJ Tsai

L-deprenyl (selegiline) decreases excitatory synaptic transmission in the rat hippocampus via a dopaminergic mechanism
J Pharmacol Exp Ther 1996 279: 740-747. [Abstract] [PDF]  

M De Ryck, R Keersmaekers, H Duytschaever, C Claes, G Clincke, M Janssen, and G Van Reet

Lubeluzole protects sensorimotor function and reduces infarct size in a photochemical stroke model in rats
J Pharmacol Exp Ther 1996 279: 748-758. [Abstract] [PDF]  

AS Lesage, L Peeters, and JE Leysen

Lubeluzole, a novel long-term neuroprotectant, inhibits the glutamate- activated nitric oxide synthase pathway
J Pharmacol Exp Ther 1996 279: 759-766. [Abstract] [PDF]  

TJ Cicero, B Nock, and ER Meyer

Gender-related differences in the antinociceptive properties of morphine
J Pharmacol Exp Ther 1996 279: 767-773. [Abstract] [PDF]  

Y Kwon, RD Lee, and ME Morris

Hepatic uptake of choline in rat liver basolateral and canalicular membrane vesicle preparations
J Pharmacol Exp Ther 1996 279: 774-781. [Abstract] [PDF]  

P Mazzola-Pomietto, CS Aulakh, SJ Huang, and DL Murphy

Repeated administration of meta-chlorophenylpiperazine or 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane produces tolerance to its stimulatory effect on adrenocorticotropin hormone but not prolactin or corticosterone secretion in rats
J Pharmacol Exp Ther 1996 279: 782-789. [Abstract] [PDF]  

MA Bowman, OG Simell, AB Peck, J Cornelius, R Luchetta, Z Look, NK Maclaren, and MA Atkinson

Pharmacokinetics of aminoguanidine administration and effects on the diabetes frequency in nonobese diabetic mice
J Pharmacol Exp Ther 1996 279: 790-794. [Abstract] [PDF]  

CH Yang, MH Shyr, PP Tan, and SH Chan

Participation of AT1 and AT2 receptors in the differential interaction between angiotensin II or III and alpha-2 adrenoceptors in the nucleus reticularis gigantocellularis in cardiovascular regulation and antinociception in rats
J Pharmacol Exp Ther 1996 279: 795-802. [Abstract] [PDF]  

A Hoogerkamp, RH Arends, AM Bomers, JW Mandema, RA Voskuyl, and M Danhof

Pharmacokinetic/pharmacodynamic relationship of benzodiazepines in the direct cortical stimulation model of anticonvulsant effect
J Pharmacol Exp Ther 1996 279: 803-812. [Abstract] [PDF]  

LJ Janssen and J Wattie

Non-neurogenic electrically evoked relaxation in canine airway muscle involves action of free radicals on K+ channels
J Pharmacol Exp Ther 1996 279: 813-821. [Abstract] [PDF]  

M Mukai, K Kushiku, H Yamada, K Yamada, K Dan, and T Furukawa

The inhibition of ganglionic transmission via presynaptic dopamine DA1 and postsynaptic DA2 receptor activation in the canine cardiac sympathetic ganglia
J Pharmacol Exp Ther 1996 279: 822-829. [Abstract] [PDF]  

Y Nomura, M Asano, K Ito, Y Uyama, Y Imaizumi, and M Watanabe

Superficial sarcoplasmic reticulum calcium buffering of resting, voltage-dependent Ca++ influx in rat femoral arterial smooth muscle
J Pharmacol Exp Ther 1996 279: 830-837. [Abstract] [PDF]  

K Minami, N Yanagihara, K Segawa, T Sata, M Tsutsui, A Shigematsu, and F Izumi

Inhibition by protamine of catecholamine secretion and ion influxes in bovine adrenal medullary cells in culture
J Pharmacol Exp Ther 1996 279: 838-843. [Abstract] [PDF]  

GN Tseng, B Zhu, S Ling, and JA Yao

Quinidine enhances and suppresses Kv1.2 from outside and inside the cell, respectively
J Pharmacol Exp Ther 1996 279: 844-855. [Abstract] [PDF]  

JA Yao, EJ Trybulski, and GN Tseng

Quinidine preferentially blocks the slow delayed rectifier potassium channel in the rested state
J Pharmacol Exp Ther 1996 279: 856-864. [Abstract] [PDF]  

GN Tseng, M Jiang, and JA Yao

Reverse use dependence of Kv4.2 blockade by 4-aminopyridine
J Pharmacol Exp Ther 1996 279: 865-876. [Abstract] [PDF]  

M Murakami, M Kinukawa, T Kanazawa, K Maruyama, M Miyagi, H Miyata, and A Ujiie

Effects of the new class I antiarrhythmic agent Ro 22-9194, (2R)-2- amino-N-(2,6-dimethylphenyl)-N-[3-(3-pyridyl)propyl]propionamide D- tartrate, on ischemia- and reperfusion-induced arrhythmias in dogs: involvement of thromboxane A2 synthase inhibitory activity
J Pharmacol Exp Ther 1996 279: 877-883. [Abstract] [PDF]  

C Ghelardini, N Galeotti, M Figini, A Imperato, M Nicolodi, F Sicuteri, GL Gessa, and A Bartolini

The central cholinergic system has a role in the antinociception induced in rodents and guinea pigs by the antimigraine drug sumatriptan
J Pharmacol Exp Ther 1996 279: 884-890. [Abstract] [PDF]  

H Wiegand, LJ McIntosh, U Gotzsch, and U Kramer

Effects of tetrandrine on spontaneous and evoked release of acetylcholine at the mouse neuromuscular junction
J Pharmacol Exp Ther 1996 279: 891-901. [Abstract] [PDF]  

M Lefebvre, G Caille, and P du Souich

Organ-specific pattern of inhibition of diltiazem metabolism at steady state in rabbits
J Pharmacol Exp Ther 1996 279: 902-907. [Abstract] [PDF]  

P Singh and MS Roberts

Local deep tissue penetration of compounds after dermal application: structure-tissue penetration relationships
J Pharmacol Exp Ther 1996 279: 908-917. [Abstract] [PDF]  

TS Peters and SJ Lewis

Lipopolysaccharide inhibits acetylcholine- and nitric oxide-mediated vasodilation in vivo
J Pharmacol Exp Ther 1996 279: 918-925. [Abstract] [PDF]  

C Trankle, E Kostenis, U Burgmer, and K Mohr

Search for lead structures to develop new allosteric modulators of muscarinic receptors
J Pharmacol Exp Ther 1996 279: 926-933. [Abstract] [PDF]  

ER Butelman, JW Lewis, and JH Woods

Methoclocinnamox: agonist and antagonist effects of a novel long- lasting opioid in rhesus monkeys
J Pharmacol Exp Ther 1996 279: 934-938. [Abstract] [PDF]  

AJ Fischman, AA Bonab, JW Babich, NM Alpert, SL Rauch, DR Elmaleh, TM Shoup, SA Williams, and RH Rubin

Positron emission tomographic analysis of central 5-hydroxytryptamine2 receptor occupancy in healthy volunteers treated with the novel antipsychotic agent, ziprasidone
J Pharmacol Exp Ther 1996 279: 939-947. [Abstract] [PDF]  

FC Barone, AH Nelson, EH Ohlstein, RN Willette, JE Sealey, JH Laragh, WG Jr Campbell, and GZ Feuerstein

Chronic carvedilol reduces mortality and renal damage in hypertensive stroke-prone rats
J Pharmacol Exp Ther 1996 279: 948-955. [Abstract] [PDF]  

JD Winkler, T Eris, CM Sung, M Chabot-Fletcher, RJ Mayer, ME Surette, and FH Chilton

Inhibitors of coenzyme A-independent transacylase induce apoptosis in human HL-60 cells
J Pharmacol Exp Ther 1996 279: 956-966. [Abstract] [PDF]  

TP Abrahams, W Liu, and KJ Varner

Blockade of alpha-2 adrenergic receptors in the rostral ventrolateral medulla attenuates the sympathoinhibitory response to cocaine
J Pharmacol Exp Ther 1996 279: 967-974. [Abstract] [PDF]  

S Takahashi and S Okabe

The cytoprotective effect of leminoprazole on indomethacin-induced damage to rabbit gastric mucosal cells
J Pharmacol Exp Ther 1996 279: 975-982. [Abstract] [PDF]  

S Kim, A Hamaguchi, T Shinkawa, Y Kato, N Tsuchiya, K Miura, K Ohta, and H Iwao

Molecular effects of M17055, furosemide and thiazide on cardiac hypertrophy of spontaneously hypertensive rats
J Pharmacol Exp Ther 1996 279: 983-990. [Abstract] [PDF]  

AK Agrawal and BH Shapiro

Imprinted overinduction of hepatic CYP2B1 and 2B2 in adult rats neonatally exposed to phenobarbital
J Pharmacol Exp Ther 1996 279: 991-999. [Abstract] [PDF]  

JA Fox, TE Hotaling, C Struble, J Ruppel, DJ Bates, and MB Schoenhoff

Tissue distribution and complex formation with IgE of an anti-IgE antibody after intravenous administration in cynomolgus monkeys
J Pharmacol Exp Ther 1996 279: 1000-1008. [Abstract] [PDF]  

P Harvie, RF Omar, N Dusserre, N Lansac, A Desormeaux, P Gourde, M Simard, M Tremblay, D Beauchamp, and MG Bergeron

Ribavirin potentiates the efficacy and toxicity of 2',3'- dideoxyinosine in the murine acquired immunodeficiency syndrome model
J Pharmacol Exp Ther 1996 279: 1009-1017. [Abstract] [PDF]  

DT Vistica, S Kenney, M Hursey, and MR Boyd

Role of membrane potential in the accumulation of quaternized ellipticines by human tumor cell lines
J Pharmacol Exp Ther 1996 279: 1018-1025. [Abstract] [PDF]  

VR Muzykantov, ES Barnathan, EN Atochina, A Kuo, SM Danilov, and AB Fisher

Targeting of antibody-conjugated plasminogen activators to the pulmonary vasculature
J Pharmacol Exp Ther 1996 279: 1026-1034. [Abstract] [PDF]  

Q Li, NA Muma, and LD van de Kar

Chronic fluoxetine induces a gradual desensitization of 5-HT1A receptors: reductions in hypothalamic and midbrain Gi and G(o) proteins and in neuroendocrine responses to a 5-HT1A agonist
J Pharmacol Exp Ther 1996 279: 1035-1042. [Abstract] [PDF]  

M Sparago, J Wlos, J Yuan, G Hatzidimitriou, J Tolliver, TA Dal Cason, J Katz, and G Ricaurte

Neurotoxic and pharmacologic studies on enantiomers of the N-methylated analog of cathinone (methcathinone): a new drug of abuse
J Pharmacol Exp Ther 1996 279: 1043-1052. [Abstract] [PDF]  

KJ Salter and RZ Kozlowski

Endothelin receptor coupling to potassium and chloride channels in isolated rat pulmonary arterial myocytes
J Pharmacol Exp Ther 1996 279: 1053-1062. [Abstract] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.