PERSPECTIVES IN PHARMACOLOGY:

Edward D. French

Academic Pharmacologists: Confronting New Challenges in Educational Programs of Graduate and Health Care Professionals
J Pharmacol Exp Ther 2004 309: 441-443. Published online February 6, 2004; 10.1124/jpet.103.050237 [Abstract] [Full Text] [PDF]  

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION:

William A. Banks, Matthew J. During, and Michael L. Niehoff

Brain Uptake of the Glucagon-Like Peptide-1 Antagonist Exendin(9-39) after Intranasal Administration
J Pharmacol Exp Ther 2004 309: 469-475. Published online January 14, 2004; 10.1124/jpet.103.063222 [Abstract] [Full Text] [PDF]  

Jill S. Warrington, David J. Greenblatt, and Lisa L. von Moltke

Age-Related Differences in CYP3A Expression and Activity in the Rat Liver, Intestine, and Kidney
J Pharmacol Exp Ther 2004 309: 720-729. Published online January 23, 2004; 10.1124/jpet.103.061077 [Abstract] [Full Text] [PDF]  

Jill S. Warrington, David J. Greenblatt, and Lisa L. von Moltke

The Effect of Age on P-Glycoprotein Expression and Function in the Fischer-344 Rat
J Pharmacol Exp Ther 2004 309: 730-736. Published online February 2, 2004; 10.1124/jpet.103.061234 [Abstract] [Full Text] [PDF]  

BEHAVIORAL PHARMACOLOGY:

L. P. Carter, A. W. Unzeitig, H. Wu, W. Chen, A. Coop, W. Koek, and C. P. France

The Discriminative Stimulus Effects of -Hydroxybutyrate and Related Compounds in Rats Discriminating Baclofen or Diazepam: The Role of GABA_B and GABA_A Receptors
J Pharmacol Exp Ther 2004 309: 540-547. Published online January 23, 2004; 10.1124/jpet.103.062950 [Abstract] [Full Text] [PDF]  

Jonathan L. Katz, Theresa A. Kopajtic, Gregory E. Agoston, and Amy Hauck Newman

Effects of N-Substituted Analogs of Benztropine: Diminished Cocaine-Like Effects in Dopamine Transporter Ligands
J Pharmacol Exp Ther 2004 309: 650-660. Published online January 30, 2004; 10.1124/jpet.103.060525 [Abstract] [Full Text] [PDF]  

CARDIOVASCULAR:

Denan Jin, Shinji Takai, Masato Sakaguchi, Yukiko Okamoto, Michiko Muramatsu, and Mizuo Miyazaki

An Antiarrhythmic Effect of a Chymase Inhibitor after Myocardial Infarction
J Pharmacol Exp Ther 2004 309: 490-497. Published online January 16, 2004; 10.1124/jpet.103.061465 [Abstract] [Full Text] [PDF]  

Jean-Michel Dogné, Julien Hanson, Xavier de Leval, Philippe Kolh, Vincent Tchana-Sato, Laurence de Leval, Stéphanie Rolin, Alexandre Ghuysen, Patrick Segers, Bernard Lambermont, Bernard Masereel, and Bernard Pirotte

Pharmacological Characterization of N-tert-Butyl-N'-[2-(4'-methylphenylamino)-5-nitrobenzenesulfonyl]urea (BM-573), a Novel Thromboxane A₂ Receptor Antagonist and Thromboxane Synthase Inhibitor in a Rat Model of Arterial Thrombosis and Its Effects on Bleeding Time
J Pharmacol Exp Ther 2004 309: 498-505. Published online January 23, 2004; 10.1124/jpet.103.063610 [Abstract] [Full Text] [PDF]  

Peter S. Fischbach, Andrew White, Terrance D. Barrett, and Benedict R. Lucchesi

Risk of Ventricular Proarrhythmia with Selective Opening of the Myocardial Sarcolemmal versus Mitochondrial ATP-Gated Potassium Channel
J Pharmacol Exp Ther 2004 309: 554-559. Published online January 27, 2004; 10.1124/jpet.103.060780 [Abstract] [Full Text] [PDF]  

Chun-Mei Cao, Qiang Xia, Jie Tu, Mai Chen, Song Wu, and Tak-Ming Wong

Cardioprotection of Interleukin-2 Is Mediated via -Opioid Receptors
J Pharmacol Exp Ther 2004 309: 560-567. Published online January 27, 2004; 10.1124/jpet.103.061135 [Abstract] [Full Text] [PDF]  

Cleber E. Teixeira, Juliana S. Baracat, Angelina Zanesco, Edson Antunes, and Gilberto De Nucci

Atypical -Adrenoceptor Subtypes Mediate Relaxations of Rabbit Corpus Cavernosum
J Pharmacol Exp Ther 2004 309: 587-593. Published online January 29, 2004; 10.1124/jpet.103.062026 [Abstract] [Full Text] [PDF]  

Kokichi Suzuki, Yuko Muto, Kenichi Fushihara, Ken-ichi Kanemoto, Hiroyuki Iida, Eriko Sato, Chika Kikuchi, Tetsuya Matsushima, Emiko Kato, Masahiro Nomoto, Shin Yoshioka, and Hidemi Ishii

Enhancement of Fibrinolysis by EF6265 [(S)-7-Amino-2-[[[(R)-2-methyl-1-(3-phenylpropanoylamino)propyl]hydroxyphosphinoyl] methyl]heptanoic Acid], a Specific Inhibitor of Plasma Carboxypeptidase B
J Pharmacol Exp Ther 2004 309: 607-615. Published online February 4, 2004; 10.1124/jpet.103.062729 [Abstract] [Full Text] [PDF]  

Kenji Okajima, Naoaki Harada, Mitsuhiro Uchiba, and Hirotaka Isobe

Activation of Capsaicin-Sensitive Sensory Neurons by Carvedilol, a Nonselective -Blocker, in Spontaneous Hypertensive Rats
J Pharmacol Exp Ther 2004 309: 684-691. Published online February 5, 2004; 10.1124/jpet.103.061150 [Abstract] [Full Text] [PDF]  

Anna Rab, Susanne Dallinger, Kaija Polak, Johannes Pleiner, Elzbieta Polska, Michael Wolzt, and Leopold Schmetterer

Specific Endothelin ET_A Receptor Antagonism Does Not Modulate Insulin-Induced Hemodynamic Effects in the Human Kidney, Eye, or Forearm
J Pharmacol Exp Ther 2004 309: 692-696. Published online February 2, 2004; 10.1124/jpet.103.059444 [Abstract] [Full Text] [PDF]  

M. Forrest, S.-Y. Sun, R. Hajdu, J. Bergstrom, D. Card, G. Doherty, J. Hale, C. Keohane, C. Meyers, J. Milligan, S. Mills, N. Nomura, H. Rosen, M. Rosenbach, G.-J. Shei, I. I. Singer, M. Tian, S. West, V. White, J. Xie, R. L. Proia, and S. Mandala

Immune Cell Regulation and Cardiovascular Effects of Sphingosine 1-Phosphate Receptor Agonists in Rodents Are Mediated via Distinct Receptor Subtypes
J Pharmacol Exp Ther 2004 309: 758-768. Published online January 27, 2004; 10.1124/jpet.103.062828 [Abstract] [Full Text] [PDF]  

Naoyuki Matsuda, Subrina Jesmin, Yoshika Takahashi, Eiichiro Hatta, Masanobu Kobayashi, Kazuto Matsuyama, Nozomi Kawakami, Ichiro Sakuma, Satoshi Gando, Hiyoyuki Fukui, Yuichi Hattori, and Roberto Levi

Histamine H₁ and H₂ Receptor Gene and Protein Levels Are Differentially Expressed in the Hearts of Rodents and Humans
J Pharmacol Exp Ther 2004 309: 786-795. Published online January 29, 2004; 10.1124/jpet.103.063065 [Abstract] [Full Text] [PDF]  

Anindya Bhattacharya, Kathryn W. Schenck, Yao-Chang Xu, Laura Nisenbaum, Elizabeth Galbreath, and Marlene L. Cohen

5-Hydroxytryptamine_1B Receptor-Mediated Contraction of Rabbit Saphenous Vein and Basilar Artery: Role of Vascular Endothelium
J Pharmacol Exp Ther 2004 309: 825-832. Published online January 14, 2004; 10.1124/jpet.103.062653 [Abstract] [Full Text] [PDF]  

Wei Ni, Melissa W. Li, Keshari Thakali, Gregory D. Fink, and Stephanie W. Watts

The Fenfluramine Metabolite (+)-Norfenfluramine Is Vasoactive
J Pharmacol Exp Ther 2004 309: 845-852. Published online January 29, 2004; 10.1124/jpet.103.060806 [Abstract] [Full Text] [PDF]  

CELLULAR AND MOLECULAR:

Craig E. Crosson, Phillip W. Yates, Aruna N. Bhat, Yurii V. Mukhin, and Shahid Husain

Evidence for Multiple P2Y Receptors in Trabecular Meshwork Cells
J Pharmacol Exp Ther 2004 309: 484-489. Published online January 23, 2004; 10.1124/jpet.103.060319 [Abstract] [Full Text] [PDF]  

Brice Marcet, Valérie Chappe, Patrick Delmas, and Bernard Verrier

Pharmacological and Signaling Properties of Endogenous P2Y1 Receptors in Cystic Fibrosis Transmembrane Conductance Regulator-Expressing Chinese Hamster Ovary Cells
J Pharmacol Exp Ther 2004 309: 533-539. Published online January 23, 2004; 10.1124/jpet.103.063396 [Abstract] [Full Text] [PDF]  

Charlotta Liljebris, Pawel Baranczewski, Eva Björkstrand, Styrbjörn Byström, Bo Lundgren, Agneta Tjernberg, Malin Warolén, and Stephen R. James

Oxidation of Protein Tyrosine Phosphatases as a Pharmaceutical Mechanism of Action: A Study Using 4-Hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione
J Pharmacol Exp Ther 2004 309: 711-719. Published online January 27, 2004; 10.1124/jpet.103.062745 [Abstract] [Full Text] [PDF]  

I. Matias, J. Chen, L. De Petrocellis, T. Bisogno, A. Ligresti, F. Fezza, A.H.-P. Krauss, L. Shi, C. E. Protzman, C. Li, Y. Liang, A. L. Nieves, K. M. Kedzie, R. M. Burk, V. Di Marzo, and D. F. Woodward

Prostaglandin Ethanolamides (Prostamides): In Vitro Pharmacology and Metabolism
J Pharmacol Exp Ther 2004 309: 745-757. Published online February 2, 2004; 10.1124/jpet.103.061705 [Abstract] [Full Text] [PDF]  

Daniela A. Eisinger and Rüdiger Schulz

Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinases Block Internalization of -Opioid Receptors
J Pharmacol Exp Ther 2004 309: 776-785. Published online January 23, 2004; 10.1124/jpet.103.061788 [Abstract] [Full Text] [PDF]  

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY:

Charlene R. Johnson, Jiong Chun, Robert Bittman, and W. David Jarvis

Intrinsic Cytotoxicity and Chemomodulatory Actions of Novel Phenethylisothiocyanate Sphingoid Base Derivatives in HL-60 Human Promyelocytic Leukemia Cells
J Pharmacol Exp Ther 2004 309: 452-461. Published online January 14, 2004; 10.1124/jpet.103.060665 [Abstract] [Full Text] [PDF]  

Qiwei Zhang, David W. Ohannesian, and Leonard C. Erickson

Hammerhead Ribozyme-Mediated Sensitization of Human Tumor Cells after Treatment with 1,3-Bis(2-chloroethyl)-1-nitrosourea
J Pharmacol Exp Ther 2004 309: 506-514. Published online January 23, 2004; 10.1124/jpet.103.061507 [Abstract] [Full Text] [PDF]  

Amanda P. Struckhoff, Robert Bittman, Matthew E. Burow, Sanda Clejan, Steven Elliott, Timothy Hammond, Yan Tang, and Barbara S. Beckman

Novel Ceramide Analogs as Potential Chemotherapeutic Agents in Breast Cancer
J Pharmacol Exp Ther 2004 309: 523-532. Published online January 23, 2004; 10.1124/jpet.103.062760 [Abstract] [Full Text] [PDF]  

Edward A. Neuwelt, Michael A. Pagel, Dale F. Kraemer, Darryl R. Peterson, and Leslie L. Muldoon

Bone Marrow Chemoprotection without Compromise of Chemotherapy Efficacy in a Rat Brain Tumor Model
J Pharmacol Exp Ther 2004 309: 594-599. Published online January 29, 2004; 10.1124/jpet.103.063347 [Abstract] [Full Text] [PDF]  

ENDOCRINE AND REPRODUCTIVE:

Robert N. Pechnick and Russell E. Poland

Comparison of the Effects of Dextromethorphan, Dextrorphan, and Levorphanol on the Hypothalamo-Pituitary-Adrenal Axis
J Pharmacol Exp Ther 2004 309: 515-522. Published online January 23, 2004; 10.1124/jpet.103.060038 [Abstract] [Full Text] [PDF]  

David E. Potter, Karen R. M. Russell, and Marlina Manhiani

Bremazocine Increases C-Type Natriuretic Peptide Levels in Aqueous Humor and Enhances Outflow Facility
J Pharmacol Exp Ther 2004 309: 548-553. Published online January 23, 2004; 10.1124/jpet.103.063107 [Abstract] [Full Text] [PDF]  

Shuhei Tomimoto, Hitoshi Hashimoto, Norihito Shintani, Kyohei Yamamoto, Yuki Kawabata, Ken-Ichi Hamagami, Kazuya Yamagata, Jun-Ichiro Miyagawa, and Akemichi Baba

Overexpression of Pituitary Adenylate Cyclase-Activating Polypeptide in Islets Inhibits Hyperinsulinemia and Islet Hyperplasia in Agouti Yellow Mice
J Pharmacol Exp Ther 2004 309: 796-803. Published online January 23, 2004; 10.1124/jpet.103.062919 [Abstract] [Full Text] [PDF]  

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL:

Niel C. Hoglen, Long-Shiuh Chen, Craig D. Fisher, Brad P. Hirakawa, Todd Groessl, and Patricia C. Contreras

Characterization of IDN-6556 (3-{2-(2-tert-Butyl-phenylaminooxalyl)-amino]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic Acid): a Liver-Targeted Caspase Inhibitor
J Pharmacol Exp Ther 2004 309: 634-640. Published online January 23, 2004; 10.1124/jpet.103.062034 [Abstract] [Full Text] [PDF]  

Osamu Handa, Yuji Naito, Tomohisa Takagi, Makoto Shimozawa, Satoshi Kokura, Norimasa Yoshida, Hirofumi Matsui, Gediminas Cepinskas, Peter R. Kvietys, and Toshikazu Yoshikawa

Tumor Necrosis Factor--Induced Cytokine-Induced Neutrophil Chemoattractant-1 (CINC-1) Production by Rat Gastric Epithelial Cells: Role of Reactive Oxygen Species and Nuclear Factor-B
J Pharmacol Exp Ther 2004 309: 670-676. Published online January 27, 2004; 10.1124/jpet.103.062216 [Abstract] [Full Text] [PDF]  

Linda Yip and Yin Nam Kwok

Role of Adenosine A_2A Receptor in the Regulation of Gastric Somatostatin Release
J Pharmacol Exp Ther 2004 309: 804-815. Published online January 23, 2004; 10.1124/jpet.103.061986 [Abstract] [Full Text] [PDF]  

INFLAMMATION AND IMMUNOPHARMACOLOGY:

Genya Gekker, Shuxian Hu, Mark P. Wentland, Jean M. Bidlack, James R. Lokensgard, and Phillip K. Peterson

-Opioid Receptor Ligands Inhibit Cocaine-Induced HIV-1 Expression in Microglial Cells
J Pharmacol Exp Ther 2004 309: 600-606. Published online February 2, 2004; 10.1124/jpet.103.060160 [Abstract] [Full Text] [PDF]  

John L. Wallace, Marcelo N. Muscará, Gilberto de Nucci, Stella Zamuner, Giuseppe Cirino, Piero del Soldato, and Ennio Ongini

Gastric Tolerability and Prolonged Prostaglandin Inhibition in the Brain with a Nitric Oxide-Releasing Flurbiprofen Derivative, NCX-2216 [3-[4-(2-Fluoro--methyl-[1,1'-biphenyl]-4-acetyloxy)-3-methoxyphenyl]-2-propenoic acid 4-nitrooxy butyl ester]
J Pharmacol Exp Ther 2004 309: 626-633. Published online January 30, 2004; 10.1124/jpet.103.063453 [Abstract] [Full Text] [PDF]  

Jean Gougat, Bernard Ferrari, Lionel Sarran, Claudine Planchenault, Martine Poncelet, Jeanne Maruani, Richard Alonso, Annie Cudennec, Tiziano Croci, Fabio Guagnini, Katalin Urban-Szabo, Jean-Pierre Martinolle, Philippe Soubrié, Olivier Finance, and Gérard Le Fur

SSR240612 [(2R)-2-[((3R)-3-(1,3-Benzodioxol-5-yl)-3-{[(6-methoxy-2-naphthyl)sulfonyl]amino}propanoyl)amino]-3-(4-{[2R,6S)-2,6-dimethylpiperidinyl]methyl}phenyl)-N-isopropyl-N-methylpropanamide Hydrochloride], a New Nonpeptide Antagonist of the Bradykinin B₁ Receptor: Biochemical and Pharmacological Characterization
J Pharmacol Exp Ther 2004 309: 661-669. Published online January 27, 2004; 10.1124/jpet.103.059527 [Abstract] [Full Text] [PDF]  

Cuifen Hou, Thomas Kirchner, Monica Singer, Michele Matheis, Dennis Argentieri, and Druie Cavender

In Vivo Activity of a Phospholipase C Inhibitor, 1-(6-((17-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione (U73122), in Acute and Chronic Inflammatory Reactions
J Pharmacol Exp Ther 2004 309: 697-704. Published online January 16, 2004; 10.1124/jpet.103.060574 [Abstract] [Full Text] [PDF]  

Chang Seok Park, Hyun Lim, Kee Jung Han, Sun Heum Baek, Hyung Ok Sohn, Dong Wook Lee, Yang-Gyun Kim, Hye-Young Yun, Kwang Jin Baek, and Nyoun Soo Kwon

Inhibition of Nitric Oxide Generation by 23,24-Dihydrocucurbitacin D in Mouse Peritoneal Macrophages
J Pharmacol Exp Ther 2004 309: 705-710. Published online January 29, 2004; 10.1124/jpet.103.063693 [Abstract] [Full Text] [PDF]  

Koremu K. Meja, Matthew C. Catley, Lisa M. Cambridge, Peter J. Barnes, Hazel Lum, Robert Newton, and Mark A. Giembycz

Adenovirus-Mediated Delivery and Expression of a cAMP-Dependent Protein Kinase Inhibitor Gene to BEAS-2B Epithelial Cells Abolishes the Anti-Inflammatory Effects of Rolipram, Salbutamol, and Prostaglandin E₂: A Comparison with H-89
J Pharmacol Exp Ther 2004 309: 833-844. Published online January 27, 2004; 10.1124/jpet.103.060020 [Abstract] [Full Text] [PDF]  

NEUROPHARMACOLOGY:

Kar-Chan Choong and Roh-Yu Shen

Methylphenidate Restores Ventral Tegmental Area Dopamine Neuron Activity in Prenatal Ethanol-Exposed Rats by Augmenting Dopamine Neurotransmission
J Pharmacol Exp Ther 2004 309: 444-451. Published online January 14, 2004; 10.1124/jpet.103.060657 [Abstract] [Full Text] [PDF]  

Francesco Crespi and Zvani L. Rossetti

Pulse of Nitric Oxide Release in Response to Activation of N-Methyl-D-aspartate Receptors in the Rat Striatum: Rapid Desensitization, Inhibition by Receptor Antagonists, and Potentiation by Glycine
J Pharmacol Exp Ther 2004 309: 462-468. Published online January 14, 2004; 10.1124/jpet.103.061069 [Abstract] [Full Text] [PDF]  

Thomas F. Finnegan, De-Pei Li, Shao-Rui Chen, and Hui-Lin Pan

Activation of µ-Opioid Receptors Inhibits Synaptic Inputs to Spinally Projecting Rostral Ventromedial Medulla Neurons
J Pharmacol Exp Ther 2004 309: 476-483. Published online January 14, 2004; 10.1124/jpet.103.064808 [Abstract] [Full Text] [PDF]  

Julie A. O'Brien, Wei Lemaire, Marion Wittmann, Marlene A. Jacobson, Sookhee N. Ha, David D. Wisnoski, Craig W. Lindsley, Hervé J. Schaffhauser, Blake Rowe, Cyrille Sur, Mark E. Duggan, Douglas J. Pettibone, P. Jeffrey Conn, and David L. Williams, Jr.

A Novel Selective Allosteric Modulator Potentiates the Activity of Native Metabotropic Glutamate Receptor Subtype 5 in Rat Forebrain
J Pharmacol Exp Ther 2004 309: 568-577. Published online January 27, 2004; 10.1124/jpet.103.061747 [Abstract] [Full Text] [PDF]  

Kamisha L. Johnson-Davis, Jannine G. Truong, Annette E. Fleckenstein, and Diana G. Wilkins

Alterations in Vesicular Dopamine Uptake Contribute to Tolerance to the Neurotoxic Effects of Methamphetamine
J Pharmacol Exp Ther 2004 309: 578-586. Published online January 27, 2004; 10.1124/jpet.103.062695 [Abstract] [Full Text] [PDF]  

Sarah M. Sweitzer, Shirley M. E. Wong, Michael C. Peters, Daria Mochly-Rosen, David C. Yeomans, and Joan J. Kendig

Protein Kinase C and : Involvement in Formalin-Induced Nociception in Neonatal Rats
J Pharmacol Exp Ther 2004 309: 616-625. Published online February 4, 2004; 10.1124/jpet.103.060350 [Abstract] [Full Text] [PDF]  

Kyung-Chul Woo, Yong-Soo Park, Dong-Jae Jun, Jeong-Ok Lim, Woon-Yi Baek, Byung-Sun Suh, and Kyong-Tai Kim

Phytoestrogen Cimicifugoside-Mediated Inhibition of Catecholamine Secretion by Blocking Nicotinic Acetylcholine Receptor in Bovine Adrenal Chromaffin Cells
J Pharmacol Exp Ther 2004 309: 641-649. Published online February 2, 2004; 10.1124/jpet.103.062331 [Abstract] [Full Text] [PDF]  

Eric B. Gonzales, Cathy L. Bell-Horner, Maria Antonette M. de la Cruz, James A. Ferrendelli, Douglas F. Covey, and Glenn H. Dillon

Enantioselectivity of -Benzyl--methyl--butyrolactone-Mediated Modulation of Anticonvulsant Activity and GABA_A Receptor Function
J Pharmacol Exp Ther 2004 309: 677-683. Published online January 23, 2004; 10.1124/jpet.103.063008 [Abstract] [Full Text] [PDF]  

Makoto Nakagawa, Makoto Ohgoh, Yukio Nishizawa, and Hiroo Ogura

Dopaminergic Agonists and Muscarinic Antagonists Improve Lateralization in Hemiparkinsonian Rats in a Novel Exploratory Y-Maze
J Pharmacol Exp Ther 2004 309: 737-744. Published online January 30, 2004; 10.1124/jpet.103.059519 [Abstract] [Full Text] [PDF]  

Joshua D. Rabinowitz, Martin Wensley, Peter Lloyd, Daniel Myers, William Shen, Amy Lu, Craig Hodges, Ron Hale, Daniel Mufson, and Alejandro Zaffaroni

Fast Onset Medications through Thermally Generated Aerosols
J Pharmacol Exp Ther 2004 309: 769-775. Published online January 29, 2004; 10.1124/jpet.103.062893 [Abstract] [Full Text] [PDF]  

Maia Terashvili, Hsiang-en Wu, Randy J. Leitermann, Kuei-chun Hung, Andrew D. Clithero, Emma T. Schwasinger, and Leon F. Tseng

Differential Conditioned Place Preference Responses to Endomorphin-1 and Endomorphin-2 Microinjected into the Posterior Nucleus Accumbens Shell and Ventral Tegmental Area in the Rat
J Pharmacol Exp Ther 2004 309: 816-824. Published online January 30, 2004; 10.1124/jpet.103.059287 [Abstract] [Full Text] [PDF]  

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